|2020年11月26日（礼拜四）下战书16:00生科楼2018 “111引智打算”专家报告（可经由过程zoom线上参与,集会ID: 294 865 7118，暗码: 963021）|
标题问题: The future of newborn screening (using WGS)
主讲人: Prof. Lennart Hammarström
（zoom集会ID: 294 865 7118，暗码: 963021）
约请人: 赵要风 62731142-2003
They have previously initiated screening for severe forms of immunodeficiency using TREC/KREC in newborns and their method which is now implemented in the Swedish national newborn screening program. They are also helping to run this in Germany, Poland, Switzerland, Iceland, the Netherlands and a few other countries. In the future, several additional diseases are expected to be screened for. Thus far, only PKU and hearing loss are regularly being screened for in Chinese newborn children. Lately, they have therefore started a pilot project running WGS on newborns in China - not only as a diagnostic service for those with a suspected disease but also on newborns who appear healthy at birth. Many mutations in essential genes have been found, prompting an expansion of the study. Although there are considerable ethical hurdles, this is the future of newborn screening.
Lennart Hammarström, Senior Professor. He started medical school (Karolinska Institutet) in 1969 and begun doing research in 1971. After finishing medical school, He went into research full time and presented my PhD thesis (on cell stimulation with mitogens) in 1979. He subsequently completed his practical medical training (AT) and started specializing in clinical immunology, becoming a specialist in 1984. Initially, He took on the post as a head of the clinical immunology laboratory (in 1997) but later devoted his time more to research and was appointed head of the division of Clinical Immunology in 1999, the same year that he became professor (and subsequently Distinguished professor, 2009) at the Karolinska Institutet.
Immunodeficiency, immunogenetics, regulation of antibody production, immunotherapy, newborn screening. Published more than 600 scientific articles in these fields (h-index (Google scholar) 89, more than 33000 citations (Google scholar)).